GTX24774
eIF4E (phospho Ser209) antibody
Cannot supply to this region.
- SKU:
- GTX24774
- Additional Names:
- eukaryotic translation initiation factor 4E , AUTS19 , CBP , EIF4E1 , EIF4EL1 , EIF4F , eIF-4E
- Application:
- Flow Cytometry, WB, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rabbit, Rat
- Buffer:
- PBS, 0.1% BSA, 50% Glycerol, 0.05% Sodium azide.
- Immunogen:
- The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human eIF4E that contains serine 209. The sequence is conserved in mouse, rat and rabbit.
- Uniprot:
- P06730
- Synonyms:
- AUTS19;CBP;eIF-4E;eIF-4F 25 kDa subunit;EIF4E1;EIF4EL1;EIF4F;eukaryotic translation initiation factor 4E;eukaryotic translation initiation factor 4E-like 1;mRNA cap-binding protein
- Extra Details:
- The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
- Shipping Conditions:
- Blue Ice