NF-L antibody [DA2]

Cannot supply to this region.

SKU:: GTX24572
Application:: ELISA, WB, IF, ICC
Physical State:: Liquid
Species Reactivity:: Porcine
Purification:: Crude Cell Culture Supernatant
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Bovine, Human, Mouse, Porcine, Rat
Buffer:: Tissue culture supernatant, no preservatives.
Immunogen:: Enzymatically dephosphorylated pig neurofilaments including NF-L, NF-M and NF-H.
Clone:: DA2
Extra Details:: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-L antibody can also be useful in the diagnostics of neurofilament accumulations seen in many neurological diseases, such as Lou Gehrig's disease or Alzheimer's disease. Mutations in the protein coding region of the human NF-L gene appear to cause some forms of Charcot-Marie-Tooth disease.