Fibrillarin antibody [38F3]

Cannot supply to this region.

SKU:: GTX24566
Additional Names:: fibrillarin , FIB , FLRN , Nop1 , RNU3IP1
Application:: IHC, WB, IHC-P, IF, ICC
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse, Plant, Rat, Yeast, Insect/Arthropod
ABP:: No Import Docs
Buffer:: Tissue culture supernatant, 10mM Sodium azide.
Immunogen:: Yeast nuclear preparation (S. cerevisiae).Hybridomas were screened by immunofluorescence on yeast cells and by western blotting on yeast protein homogenates (S. cerevisiae).
Clone:: 38F3
Uniprot:: P22087
Synonyms:: 34 kDa nucleolar scleroderma antigen;34-kD nucleolar scleroderma antigen;FIB;FLRN;histone-glutamine methyltransferase;Nop1;RNA, U3 small nucleolar interacting protein 1;RNU3IP1;rRNA 2'-O-methyltransferase fibrillarin;U6 snRNA 2'-O-methyltransferase fibrillarin
Extra Details:: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice