E2F1 antibody [KH95]

Cannot supply to this region.

SKU:: GTX24070
Additional Names:: E2F transcription factor 1 , E2F-1 , RBAP1 , RBBP3 , RBP3
Application:: ChIP, WB, IHC-P, IP
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Ascites, 0.09% Sodium azide.
Immunogen:: BALB/C mice were immunized with a recombinant human E2F-1 protein.
Clone:: KH95
Uniprot:: Q01094
Synonyms:: E2F-1;PBR3;PRB-binding protein E2F-1;RBAP-1;RBAP1;RBBP-3;RBBP3;RBP3;retinoblastoma-associated protein 1;retinoblastoma-binding protein 3;transcription factor E2F1
Extra Details:: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice