GTX23499
LDB1 antibody
Cannot supply to this region.
- SKU:
- GTX23499
- Additional Names:
- LIM domain binding 1 , CLIM2 , NLI
- Application:
- ChIP, ELISA, WB
- Concentration:
- 1.8 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human, Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding to a C-Terminal region of mouse LDB1 protein.
- Uniprot:
- P70662
- Synonyms:
- carboxyl-terminal LIM domain-binding protein 2;CLI;CLIM2;LIM domain-binding factor CLIM2;LIM domain-binding protein 1;NLI;nuclear LIM interactor
- Extra Details:
- The LIM-domain binding protein binds to the LIM domain of LIM homeodomain proteins which are transcriptional regulators of development. Nuclear LIM interactor (NLI) / LIM domain-binding protein 1 (LDB 1) is located in the nuclei of neuronal cells during development, it is co-expressed with Isl1 in early motor neuron differentiation and has a suggested role in the Isl1 dependent development of motor neurons. It is suggested that these proteins act synergistically to enhance transcriptional efficiency by acting as co-factors for LIM homeodomain and Otx class transcription factors both of which have essential roles in development.
- Shipping Conditions:
- Blue Ice