GTX23373
MRP2 antibody [M2III-6]
Cannot supply to this region.
- SKU:
- GTX23373
- Additional Names:
- ATP binding cassette subfamily C member 2 , ABC30 , CMOAT , DJS , MRP2 , cMRP
- Application:
- WB, IHC-P, IHC-Fr, IF, ICC
- Concentration:
- 0.1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- 2-8[o]C concentrated solution. Aliquot. Avoid freeze/thaw cycles., -20[o]C concentrated solution. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human, Rat
- Buffer:
- PBS, 1% BSA, 0.1% Sodium azide.
- Immunogen:
- Bacterial fusion protein of human MRP 2 containing the carboxy-terminal region (202-)
- Clone:
- M2III-6
- Uniprot:
- Q92887
- Synonyms:
- ABC30;ATP-binding cassette sub-family C member 2;ATP-binding cassette, sub-family C (CFTR/MRP), member 2;canalicular multidrug resistance protein;canalicular multispecific organic anion transporter 1;CMOAT;cMRP;DJS;MRP2;multidrug resistance-associated protein 2
- Extra Details:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice