GTX23340
SNAP23 antibody
Cannot supply to this region.
- SKU:
- GTX23340
- Additional Names:
- synaptosomal-associated protein 23 , 23kDa , AA408749 , SNAP-23 , Sndt , Syndet
- Application:
- Flow Cytometry, WB, IF, ICC, IP
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Bovine, Human, Mouse, Rat
- Buffer:
- PBS, 0.1% BSA, 0.05% Sodium azide.
- Immunogen:
- Sythetic Peptide: C N(193) K N R I D I A N T R A K K L I D S(210)
- Uniprot:
- O09044
- Synonyms:
- 23kDa;AA408749;Sn;SNA;SNAP-23;Sndt;synaptosomal-associated protein 23;synaptosomal-associated protein, 23kD;Synd;Syndet;vesicle-membrane fusion protein SNAP-23
- Extra Details:
- Synaptosomal-associated proteins (SNAPs) are cytosolic proteins that play a key role in in the process of membrane fusion in intracellular vesicle trafficking. In eukaryotic cells, the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex is critical to membrane docking and fusion and is believed to impart some degree of specificity between vesicle SNARE (v-SNARE) and target organelle SNARE (t-SNARE). In neurons and neuroendocrine cells, the SNARE complex consists of the integral membrane proteins VAMP (vesicle-associated membrane protein), syntaxin and SNAP-25. In non-neuronal tissue, a SNAP-25 homolog, SNAP-23, functionally replaces SNAP-25 in the SNARE complex. Studies show that VAMP, syntaxin and SNAP-23 are required for SNARE function and that this complex exists as a heterotrimer of the three proteins. In insulin signalling pathways, studies suggest that the translocation of GLUT4 in adipocytes requires that functional SNAP-23 be present in SNARE complexes.
- Shipping Conditions:
- Blue Ice