LAT antibody [LAT-01]

Cannot supply to this region.

SKU:: GTX22852
Additional Names:: LAT , LAT1 , linker for activation of Tcells , pp36 , linker for activation of T cells
Application:: Flow Cytometry, WB, IP
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 15mM Sodium azide.
Immunogen:: Bacterially produced recombinant polypeptide corresponding to the entire cytoplasmic domain of human LAT.
Clone:: LAT-01
Uniprot:: O43561
Synonyms:: 36 kDa phospho-tyrosine adapter protein;36 kDa phospho-tyrosine adaptor protein;IMD52;LAT1;linker for activation of T cells, transmembrane adaptor;linker for activation of T-cells family member 1;p36-38;pp36
Extra Details:: The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]