HIF1 beta antibody [2B10]

Cannot supply to this region.

SKU:: GTX22771
Additional Names:: aryl hydrocarbon receptor nuclear translocator , HIF-1-beta , HIF-1beta , HIF1-beta , HIF1B , HIF1BETA , TANGO , bHLHe2
Application:: IHC, WB, IHC-P, IF, ICC, IP
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Fish, Human, Mouse, Rat
Buffer:: PBS, 0.1% BSA, 0.05% Sodium azide.
Immunogen:: Synthetic peptide corresponding to residues C N(771) S Y N N E E F P D L T M F P P F S E(789) of human ARNT.
Clone:: 2B10
Uniprot:: P27540
Synonyms:: aryl hydrocarbon receptor nuclear translocator;bHLHe2;class E basic helix-loop-helix protein 2;dioxin receptor, nuclear translocator;HIF-1-beta;HIF-1beta;HIF1-beta;HIF1B;HIF1BETA;Hypoxia-inducible factor 1-beta;hypoxia-inducible factor 1, beta subunit;TANGO
Extra Details:: This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]

Shipping Conditions:: Blue Ice