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GTX22450

Diablo peptide

Cannot supply to this region.

SKU:
GTX22450
Additional Names:
diablo IAP-binding mitochondrial protein , DFNA64 , SMAC
Application:
IP
Concentration:
0.2 mg/ml
Physical State:
Liquid
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Genetex
Buffer:
PBS, BSA, 0.1% Sodium azide.
Immunogen:
diablo IAP-binding mitochondrial protein
Species:
Human
Uniprot:
Q9NR28
Synonyms:
DFNA64;diablo homolog, mitochondrial;diablo-like protein;direct IAP-binding protein with low pI;second mitochondria-derived activator of caspase;SMAC
Extra Details:
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Shipping Conditions:
Blue Ice