GTX22448
Diablo antibody
Cannot supply to this region.
- SKU:
- GTX22448
- Additional Names:
- diablo IAP-binding mitochondrial protein , DFNA64 , SMAC
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.2% Gelatin, 0.1% Sodium azide.
- Immunogen:
- Peptide mapping to the carboxy terminus of human Smac/DIABLO.
- Uniprot:
- Q9NR28
- Synonyms:
- DFNA64;diablo homolog, mitochondrial;diablo-like protein;direct IAP-binding protein with low pI;second mitochondria-derived activator of caspase;SMAC
- Extra Details:
- This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
- Shipping Conditions:
- Blue Ice