MVP/LRP antibody [1032]

Cannot supply to this region.

SKU:: GTX22376
Additional Names:: major vault protein , LRP , VAULT1
Application:: IHC, WB, IHC-P, IP
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Purified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Rat
Buffer:: PBS, 0.09% Sodium azide.
Immunogen:: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells.
Clone:: 1032
Uniprot:: Q14764
Synonyms:: LRP;lung resistance-related protein;major vault protein;testicular secretory protein Li 30;VAULT1
Extra Details:: This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]