GTX22237
SIAH1 antibody
Cannot supply to this region.
- SKU:
- GTX22237
- Additional Names:
- siah E3 ubiquitin protein ligase 1 , SIAH1A
- Application:
- WB, IP
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human, Mouse, Rat, Insect/Arthropod
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence SRQTATALPTGTSKC, from the N Terminus of the protein sequence according to NP_003022.3; NP_001006611.1.
- Uniprot:
- Q8IUQ4
- Synonyms:
- BURHAS;E3 ubiquitin-protein ligase SIAH1;RING-type E3 ubiquitin transferase SIAH1;seven in absentia homolog 1;siah-1a;SIAH1A
- Extra Details:
- This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice