SIAH1 blocking peptide

Cannot supply to this region.

SKU:: GTX22237-PEP
Additional Names:: Siah E3 Ubiquitin Protein Ligase 1 , Siah1A , Siah1
Physical State:: Lyophilized
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
Immunogen:: siah E3 ubiquitin protein ligase 1
Species:: Human
Synonyms:: BURHAS;E3 ubiquitin-protein ligase SIAH1;RING-type E3 ubiquitin transferase SIAH1;seven in absentia homolog 1;siah-1a;SIAH1A
Extra Details:: This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]