GTX22012
Caspase 10 antibody
Cannot supply to this region.
- SKU:
- GTX22012
- Additional Names:
- ALPS2 , CASP10 , FLICE2 , MCH4 , caspase 10 , Caspase 10
- Application:
- ELISA, WB, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Peptide corresponding to aa 505-521 at C-terminus of human FLICE2 (accession no. AAD28402).
- Uniprot:
- Q92851
- Synonyms:
- ALPS2;apoptotic protease MCH-4;CASP-10;caspase 10 apoptosis-related cysteine peptidase;caspase 10, apoptosis-related cysteine protease;caspase-10;FADD-like ICE2;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE-2;FLICE2;ICE-like apoptotic protease 4;interleukin-1B-converting enzyme 2;MCH4
- Extra Details:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
- Shipping Conditions:
- Blue Ice