CD3 antibody

Cannot supply to this region.

SKU:: GTX20828
Additional Names:: CD3d molecule , CD3-DELTA , IMD19 , T3D
Application:: IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Purified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 0.09% Sodium azide.
Immunogen:: Synthetic human CD3 polypeptide conjugated to bovine serum albumin.
Uniprot:: P04234
Synonyms:: CD3 antigen, delta subunit;CD3 delta;CD3-DELTA;CD3d antigen, delta polypeptide (TiT3 complex);CD3d molecule, delta (CD3-TCR complex);IMD19;OKT3, delta chain;T-cell receptor T3 delta chain;T-cell surface glycoprotein CD3 delta chain;T3D
Extra Details:: The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]