GTX20259
CHAC1 antibody, C-term
Cannot supply to this region.
- SKU:
- GTX20259
- Additional Names:
- ChaC glutathione specific gamma-glutamylcyclotransferase 1
- Application:
- WB
- Concentration:
- 0.5-1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a C-terminal region of Human CHAC1
- Uniprot:
- Q9BUX1
- Synonyms:
- blocks Notch protein;botch;Cation transport regulator-like protein 1;ChaC, cation transport regulator homolog 1;ChaC, cation transport regulator-like 1;gamma-GCG 1;gamma-GCT acting on glutathione homolog 1;glutathione-specific gamma-glutamylcyclotransferase 1
- Extra Details:
- This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients. [provided by RefSeq, Sep 2016]
- Shipping Conditions:
- Blue Ice