GTX18691
DNA ligase I antibody
Cannot supply to this region.
- SKU:
- GTX18691
- Additional Names:
- Dna Ligase 1 , Lig1
- Application:
- ELISA, WB
- Concentration:
- 1.1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Bovine, Human
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Full length native protein (purified) (Cow)
- Synonyms:
- DNA ligase (ATP) 1;DNA ligase 1;DNA ligase I
- Extra Details:
- Eukaryotic DNA ligases are ATP-dependent enzymes that catalyse the joining of single and double-strand DNA breaks, which is an essential final step in DNA replication, recombination and repair. Four biochemically distinct DNA ligases, termed ligases I-IV, have been identified in mammalian cells. DNA ligase I is functionally homologous to the DNA ligase encoded by the Saccharomyces cerevisiae Cdc9 gene. The joining of Okazaki fragments during lagging strand DNA replication in mammalian cells is due to DNA ligase I. A combination of DNA polymerase epsilon, PCNA, replication factor C, replication protein A, and DNA ligase I is well-suited to the task of creating nucleotide excision repair patches.
- Shipping Conditions:
- Blue Ice