![alpha Actinin 1 antibody [0.T.02]](https://www.genetex.com/upload/website/prouct_img/normal/GTX18061/GTX18061_20191203_WB_62_w_23060620_341.webp)
GTX18061
alpha Actinin 1 antibody [0.T.02]
Cannot supply to this region.
- SKU:
- GTX18061
- Additional Names:
- ACTN1 , BDPLT15 , actinin alpha 1 , alpha Actinin 1
- Application:
- WB, IHC-Fr, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 250mM NaCl, 0.1% Sodium azide.
- Immunogen:
- Human alpha-Actinin
- Clone:
- 0.T.02
- Uniprot:
- P12814
- Synonyms:
- actinin 1 smooth muscle;Alpha-actinin cytoskeletal isoform;alpha-actinin-1;BDPLT15;epididymis secretory sperm binding protein;F-actin cross-linking protein;non-muscle alpha-actinin-1
- Extra Details:
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice