OPG antibody [bony-1]

Cannot supply to this region.

SKU:: GTX18051
Additional Names:: TNF receptor superfamily member11b , OCIF , OPG , PDB5 , TNFRSF11B , TR1 , Osteoprotegerin , osteoclastogenesis inhibitory factor
Application:: Flow Cytometry, IP
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purity:: >95%
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rat
Reactivities:: Human
Buffer:: PBS, 0.02% Sodium azide.
Immunogen:: Recombinant fragment, corresponding to amino acids 22-202 of Human Osteoprotegerin.
Clone:: bony-1
Extra Details:: Osteoprotegerin (OPG) is a member of the TNF receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of the gene have been reported, but their full length nature has not been determined.