Desmoglein 3 antibody [5H10]

Cannot supply to this region.

SKU:: GTX17502
Additional Names:: desmoglein 3 , CDHF6 , PVA
Application:: WB, IHC-P, IF, ICC, IP
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Tris-Glycine, 150mM NaCl, 0.05% Sodium azide.
Immunogen:: The extracellular domain of human Desmoglein 3 [Swiss-Prot# P32926]
Clone:: 5h10
Uniprot:: P32926
Synonyms:: 130 kDa pemphigus vulgaris antigen;ABOLM;cadherin family member 6;CDHF6;desmoglein-3;PVA
Extra Details:: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq]