TGF beta Receptor antibody

Cannot supply to this region.

SKU:: GTX17282
Additional Names:: Transforming growth factor beta receptor II (70-80kDa) , TGF beta receptor , Transforming growth factor beta receptor II , TGF beta receptor type II precursor , TGF beta type II receptor , Transforming growth factor beta receptor II (7080kDa) , TGFR2
Application:: IHC, WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Sheep
Buffer:: PBS, 0.08% Sodium azide.
Immunogen:: GST fusion avian protein, containing chick transforming growth factor b type II receptor (aa 77 - 148).
Extra Details:: Three members of the TGF beta family, TGF beta 1, TGF beta 2 and TGF beta 3, are known in mammals. TGF betas mediate their activity by high affinity binding to the type 2 receptor, which requires both its kinase activity and association with members of a series of related type 1 receptors called activin receptor-like kinase (ALK) 1 to 6. Of these, only ALK5 has been shown to represent a functional TGF beta type 1 receptor, but only ALK2 and ALK4 bind activin with high affinity. TGF beta R3 binds TGF beta and retains TGF beta for presentation to the signaling receptors.