GTX17170-PEP
PHOX2A blocking peptide
Cannot supply to this region.
- SKU:
- GTX17170-PEP
- Additional Names:
- Paired Like Homeobox 2A , Arix , Cfeom2 , Feom2 , Ncam2 , Pmx2A , Phox2A
- Application:
- Neutralisation
- Concentration:
- 200 ug/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- paired like homeobox 2a
- Species:
- Human
- Synonyms:
- aristaless homeobox homolog;aristaless homeobox protein homolog;ARIX;arix homeodomain protein;ARIX1 homeodomain protein;CFEOM2;FEOM2;NCAM2;paired mesoderm homeobox protein 2A;PMX2A
- Extra Details:
- The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Dry Ice