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GTX17090-PEP

IDH2 blocking peptide

Cannot supply to this region.

SKU:
GTX17090-PEP
Additional Names:
Isocitrate Dehydrogenase (Nadp(+)) 2, Mitochondrial , D2Hga2 , Icd-M , Idh , Idhm , Idp , Idpm , Mnadp-Idh , Idh2
Application:
Neutralisation
Concentration:
200 ug/ml
Physical State:
Liquid
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Genetex
Buffer:
PBS, 0.1% BSA, 0.02% Sodium azide.
Immunogen:
isocitrate dehydrogenase 2 (NADP+), mitochondrial
Species:
Human
Synonyms:
D2HGA2;ICD-M;IDH;IDHM;IDP;IDPM;isocitrate dehydrogenase (NADP(+)) 2, mitochondrial;isocitrate dehydrogenase [NADP], mitochondrial;isocitrate dehydrogenase 2 (NADP+), mitochondrial;mNADP-IDH;NADP(+)-specific ICDH;oxalosuccinate decarboxylase
Extra Details:
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Shipping Conditions:
Dry Ice