MASP2 antibody

Cannot supply to this region.

SKU:: GTX16976
Additional Names:: mannan binding lectin serine peptidase 2 , MAP19 , MASP-2 , MASP1P1 , sMAP
Application:: WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
Immunogen:: KLH-conjugated synthetic peptide encompassing a sequence within the center region of MASP2. The exact sequence is proprietary.
Uniprot:: O00187
Synonyms:: mannan binding lectin serine peptidase 2;mannan-binding lectin serine peptidase 1 pseudogene 1;mannan-binding lectin serine protease 1 pseudogene 1;mannan-binding lectin serine protease 2;mannose-binding lectin associated protein 19;mannose-binding lectin-associated serine protease 2;mannose-binding protein-associated serine protease 2;MAP-2;MAP19;MASP-2;MASP1P1;MBL-associated plasma protein of 19 kD;MBL-associated serine protease 2;small MBL-associated protein;sMAP
Extra Details:: This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Shipping Conditions:: Blue Ice