GTX16890
IGF1R alpha + beta antibody [alphaIR3]
Cannot supply to this region.
- SKU:
- GTX16890
- Additional Names:
- insulin like growth factor 1 receptor , CD221 , IGFIR , IGFR , JTK13
- Application:
- IF, ICC, IP, Neutralisation
- Concentration:
- 0.1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- 0.05M Sodium Phosphate buffer, 0.2% Gelatin, 0.1% Sodium azide.
- Immunogen:
- Immunogen used was partially purified receptor from human placenta.
- Clone:
- alphaIR3
- Uniprot:
- P08069
- Synonyms:
- CD221;IGF-I receptor;IGFIR;IGFR;insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;JTK13;soluble IGF1R variant 1;soluble IGF1R variant 2
- Extra Details:
- This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
- Shipping Conditions:
- Blue Ice