TWEAK antibody

Cannot supply to this region.

SKU:: GTX16436
Additional Names:: TNF superfamily member 12 , APO3L , DR3LG , TNLG4A , TWEAK
Application:: WB, IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Recombinant fusion protein containing a sequence corresponding to amino acids 42-123 of human TNFSF12 (NP_003800.1).
Uniprot:: O43508
Synonyms:: APO3 ligand;APO3/DR3 ligand;APO3L;DR3LG;TNF-related WEAK inducer of apoptosis;TNFSF12-TNFSF13 protein;TNLG4A;tumor necrosis factor (ligand) superfamily, member 12;tumor necrosis factor (ligand) superfamily, member 12-member 13;tumor necrosis factor ligand 4A;tumor necrosis factor ligand superfamily member 12;tumor necrosis factor superfamily member 12;TWE-PRIL;TWEAK
Extra Details:: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]

Shipping Conditions:: Blue Ice