GTX16242
ARHGEF11 antibody
Cannot supply to this region.
- SKU:
- GTX16242
- Additional Names:
- Rho guanine nucleotide exchange factor 11 , GTRAP48 , PDZ-RHOGEF
- Application:
- WB, IHC-P
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Bovine, Canine, Human, Mouse, Rat, Equine
- Buffer:
- PBS, 0.2% Gelatin, 0.05% Sodium azide.
- Immunogen:
- A portion of amino acids 1-50 of human ARHGEF11.
- Uniprot:
- O15085
- Synonyms:
- glutamate transporter EAAT4-associated protein 48;GTRAP48;PDZ-RHOGEF;Rho guanine exchange factor (GEF) 11;Rho guanine nucleotide exchange factor (GEF) 11;rho guanine nucleotide exchange factor 11;RhoA-specific guanine nucleotide exchange factor;RhoGEF glutamate transport modulator
- Extra Details:
- Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice