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  2. Monoclonal

GTX15664

Apolipoprotein B antibody [F2C4]

Cannot supply to this region.

SKU:
GTX15664
Additional Names:
apolipoprotein B , FLDB , LDLCQ4 , apoB-100 , apoB-48
Application:
ELISA, IHC, RIA, IHC-P, IF, ICC, IP
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Ion Exchange
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
10mM Potassium Phosphate, 135mM NaCl, 2.5mM KCl, 0.1% BSA, 0.05% Sodium azide.
Immunogen:
Purified human serum LDL
Clone:
F2C4
Uniprot:
P04114
Synonyms:
apoB-100;apoB-48;apolipoprotein B (including Ag(x) antigen);apolipoprotein B-100;apolipoprotein B48;FCHL2;FLDB;LDLCQ4
Extra Details:
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice