Dysferlin antibody (Ready-to-use)

Cannot supply to this region.

SKU:: GTX15109
Additional Names:: dysferlin , FER1L1 , LGMD2B , LGMDR2 , MMD1
Application:: IHC, IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 1% BSA, 0.1% Sodium azide.
Immunogen:: Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal).
Uniprot:: O75923
Synonyms:: dysferlin;dystrophy-associated fer-1-like 1;Dystrophy-associated fer-1-like protein;fer-1-like family member 1;fer-1-like protein 1;FER1L1;LGMD2B;LGMDR2;limb girdle muscular dystrophy 2B (autosomal recessive);MMD1
Extra Details:: The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008]