GTX14558
Livin antibody
Cannot supply to this region.
- SKU:
- GTX14558
- Additional Names:
- BIRC7 , KIAP , LIVIN , MLIAP , RNF50 , baculoviral IAP repeat containing 7 , Livin
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding to aa13-30, GPQPSHWAAGDGPTQERC at the N terminus of the livin protein
- Uniprot:
- Q96CA5
- Synonyms:
- baculoviral IAP repeat-containing protein 7;KIAP;kidney inhibitor of apoptosis protein;LIVIN;livin inhibitor of apoptosis;melanoma inhibitor of apoptosis protein;ML-IAP;MLIAP;RING finger protein 50;RING-type E3 ubiquitin transferase BIRC7;RNF50
- Extra Details:
- This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013]
- Shipping Conditions:
- Blue Ice