GTX13868
TLR5 antibody
Cannot supply to this region.
- SKU:
- GTX13868
- Additional Names:
- toll like receptor 5 , MELIOS , SLE1 , SLEB1 , TIL3
- Application:
- Flow Cytometry, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein G Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Porcine, Rat
- Buffer:
- PBS, 0.05% Sodium azide.
- Immunogen:
- This antibody was developed against KLH-conjugated synthetic peptide corresponding to a portion of human TLR5 found between amino acids 300-350. It will cross-react with mouse and rat TLR5.
- Uniprot:
- O60602
- Synonyms:
- MELIOS;SLE1;SLEB1;systemic lupus erythematosus susceptibility 1;TIL3;toll-like receptor 5;toll/interleukin-1 receptor-like protein 3
- Extra Details:
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene product is expressed in myelomonocytic cells, and recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice