GTX13856
IL21 Receptor antibody
Cannot supply to this region.
- SKU:
- GTX13856
- Additional Names:
- interleukin 21 receptor , CD360 , IMD56 , NILR
- Application:
- WB
- Concentration:
- 0.5 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein G Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.2% Gelatin, 0.05% Sodium azide.
- Immunogen:
- The antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 65-80(CSLHRSAHNATHATYT) and 505-521 (CDFTSPGDEGPPRSYLR) of human IL-21R.
- Uniprot:
- Q9HBE5
- Synonyms:
- CD360;IL-21 receptor;IMD56;interleukin-21 receptor;NILR;novel interleukin receptor
- Extra Details:
- The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice