STAM antibody [29C678]

Cannot supply to this region.

SKU:: GTX13797
Additional Names:: signal transducing adaptor molecule , STAM-1 , STAM1
Application:: WB
Concentration:: 0.5 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: This antibody was developed against a synthetic peptide corresponding to amino acids 149-165 of human STAM.
Clone:: 29C678
Uniprot:: Q92783
Synonyms:: HSE1 homolog;signal transducing adapter molecule 1;signal transducing adaptor molecule (SH3 domain and ITAM motif) 1;STAM-1;STAM1
Extra Details:: This gene was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation. The encoded protein contains a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). This protein associates with JAK3 and JAK2 kinases via its ITAM region, and is phosphorylated by the JAK kinases upon cytokine stimulation, which suggests the function of this protein is as an adaptor molecule involved in the downstream signaling of cytokine receptors. HGS/HRS (hepatocyte grwoth factor-regulated tyrosine kinase substrate) has been found to bind and counteract the function of this protein. [provided by RefSeq]

Shipping Conditions:: Blue Ice