MLH1 antibody [164C819]

Cannot supply to this region.

SKU:: GTX13659
Additional Names:: mutL homolog 1 , COCA2 , FCC2 , HNPCC , HNPCC2 , hMLH1
Application:: WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Canine, Human, Mouse
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 387-403 DSREQKLDAFLQPLSKP of human MLH1; GenBank no. NP_000240.1.
Clone:: 164C819
Uniprot:: P40692
Synonyms:: COCA2;DNA mismatch repair protein Mlh1;FCC2;hMLH1;HNPCC;HNPCC2;MMRCS1;mutL homolog 1, colon cancer, nonpolyposis type 2;MutL protein homolog 1
Extra Details:: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined. [provided by RefSeq]