GTX135986
HLA-DQA1 antibody
Cannot supply to this region.
- SKU:
- GTX135986
- Additional Names:
- major histocompatibility complex, class II, DQ alpha 1 , CELIAC1 , DQ-A1 , DQA1 , HLA-DQA
- Application:
- WB, IF, ICC
- Concentration:
- 1.39 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Synthetic peptide encompassing a sequence within the Extracellular domain of human HLA-DQA1. The exact sequence is proprietary.
- Uniprot:
- P01909
- Synonyms:
- CELIAC1;DC-1 alpha chain;DC-alpha;DQ-A1;DQA1;HLA class II histocompatibility antigen DQ alpha chain;HLA class II histocompatibility antigen, DQ alpha 1 chain;HLA-DCA;HLA-DQA;MHC class II antigen DQA1;MHC class II DQ alpha chain;MHC class II DQA1;MHC class II HLA-DQ-alpha-1;MHC class II protein;MHC HLA-DQ alpha;truncated MHC class II antigen
- Extra Details:
- HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice