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GTX13573-PEP

AIRE (isoforms 1 and 2) blocking peptide

Cannot supply to this region.

SKU:
GTX13573-PEP
Additional Names:
Autoimmune Regulator , Aire1 , Apeced , Aps1 , Apsi , Pga1 , Aire
Physical State:
Lyophilized
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Buffer:
Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
Immunogen:
autoimmune regulator
Species:
Human
Synonyms:
AIRE1;APECED;APS1;APSI;autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein;autoimmune regulator;PGA1
Extra Details:
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
Shipping Conditions:
Blue Ice