GTX134606
SIRT1 antibody
Cannot supply to this region.
- SKU:
- GTX134606
- Additional Names:
- sirtuin 1 , SIR2 , SIR2L1 , SIR2alpha
- Application:
- WB, IHC-P, IF, ICC
- Concentration:
- 0.16 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- 2-8[o]C concentrated solution. Aliquot. Avoid freeze/thaw cycles., -20[o]C 50% glycerol. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the N-terminus region of human SIRT1. The exact sequence is proprietary.
- Uniprot:
- Q96EB6
- Synonyms:
- NAD-dependent protein deacetylase sirtuin-1;NAD-dependent protein deacylase sirtuin-1;regulatory protein SIR2 homolog 1;SIR2;SIR2-like protein 1;SIR2alpha;SIR2L1;sirtuin type 1
- Extra Details:
- This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
- Shipping Conditions:
- Blue Ice