GTX133807
GFI1 antibody
Cannot supply to this region.
- SKU:
- GTX133807
- Additional Names:
- growth factor independent 1 transcriptional repressor , GFI-1 , GFI1A , SCN2 , ZNF163
- Application:
- WB, IF, ICC
- Concentration:
- 1.49 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the N-terminus region of human GFI1. The exact sequence is proprietary.
- Uniprot:
- Q99684
- Synonyms:
- GFI-1;GFI1A;growth factor independence-1;growth factor independent 1 transcription repressor;growth factor independent protein 1;SCN2;zinc finger protein 163;zinc finger protein Gfi-1;ZNF163
- Extra Details:
- This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice