GTX133643
Integrin alpha 4 antibody
Cannot supply to this region.
- SKU:
- GTX133643
- Additional Names:
- integrin subunit alpha 4 , CD49D , IA4
- Application:
- WB
- Concentration:
- 1.4 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Synthetic peptide encompassing a sequence within the Intracellular domain of human Integrin alpha 4. The exact sequence is proprietary.
- Uniprot:
- P13612
- Synonyms:
- 269C wild type;alpha 4 subunit of VLA-4 receptor;antigen CD49D, alpha-4 subunit of VLA-4 receptor;CD49 antigen-like family member D;CD49D;IA4;integrin alpha-4;integrin alpha-IV;very late activation protein 4 receptor, alpha 4 subunit;VLA-4 subunit alpha
- Extra Details:
- The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
- Shipping Conditions:
- Blue Ice