GTX133564
LAMTOR4 antibody
Cannot supply to this region.
- SKU:
- GTX133564
- Additional Names:
- late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 , C7orf59
- Application:
- WB
- Concentration:
- 0.44 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Full length human LAMTOR4 recombinant protein.
- Uniprot:
- Q0VGL1
- Synonyms:
- C7orf59;late endosomal/lysosomal adaptor and MAPK and MTOR activator 4;ragulator complex protein LAMTOR4;UPF0539 protein C7orf59
- Extra Details:
- As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.1 Publication
- Shipping Conditions:
- Blue Ice