GTX13339
GRPR antibody
Cannot supply to this region.
- SKU:
- GTX13339
- Additional Names:
- gastrin releasing peptide receptor , BB2 , BB2R , GRPR
- Application:
- WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Canine, Human, Porcine, Rabbit, Equine
- Buffer:
- PBS, 0.1% Sodium azide.
- Immunogen:
- Synthetic 18 amino acid peptide from 2nd extracellular domain of human GRPR.
- Uniprot:
- P30550
- Synonyms:
- BB2;BB2R;bombesin receptor 2;BRS2;gastrin-releasing peptide receptor;GRP-preferring bombesin receptor;GRP-R
- Extra Details:
- Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice