GTX132575
Optineurin antibody
Cannot supply to this region.
- SKU:
- GTX132575
- Additional Names:
- optineurin , ALS12 , FIP2 , GLC1E , HIP7 , HYPL , NRP , TFIIIA-INTP
- Application:
- WB, IHC-P, IF, ICC, IP
- Concentration:
- 0.28 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human Optineurin. The exact sequence is proprietary.
- Uniprot:
- Q96CV9
- Synonyms:
- ALS12;E3-14.7K-interacting protein;FIP-2;FIP2;GLC1E;HIP-7;HIP7;Huntingtin interacting protein L;huntingtin yeast partner L;huntingtin-interacting protein 7;huntingtin-interacting protein L;HYPL;nemo-related protein;NRP;optic neuropathy-inducing protein;optineurin;TFIIIA-INTP;transcription factor IIIA-interacting protein;transcrption factor IIIA-interacting protein;tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains
- Extra Details:
- This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice