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  2. Polyclonal

GTX131779

CHD3 antibody

Cannot supply to this region.

SKU:
GTX131779
Additional Names:
chromodomain helicase DNA binding protein 3 , Mi-2a , Mi2-ALPHA , SNIBCPS , ZFH
Application:
WB, IHC-P, IF, ICC
Concentration:
0.76 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human CHD3. The exact sequence is proprietary.
Uniprot:
Q12873
Synonyms:
ATP-dependent helicase CHD3;CHD-3;chromodomain-helicase-DNA-binding protein 3;hZFH;mi-2 autoantigen 240 kDa protein;Mi-2a;Mi2-ALPHA;SNIBCPS;ZFH;zinc finger helicase;zinc-finger helicase (Snf2-like)
Extra Details:
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq]
Shipping Conditions:
Blue Ice