GTX131627
RIN1 antibody
Cannot supply to this region.
- SKU:
- GTX131627
- Additional Names:
- Ras and Rab interactor 1
- Application:
- WB
- Concentration:
- 1.67 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human RIN1. The exact sequence is proprietary.
- Uniprot:
- Q13671
- Synonyms:
- ras and Rab interactor 1;ras inhibitor 1;ras inhibitor JC99;ras inhibitor RIN1;ras interaction/interference protein 1
- Extra Details:
- Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
- Shipping Conditions:
- Blue Ice