MACC1 antibody

Cannot supply to this region.

SKU:: GTX131332
Additional Names:: MET transcriptional regulator MACC1 , 7A5 , SH3BP4L
Application:: WB
Concentration:: 1.14 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein encompassing a sequence within the N-terminus region of human MACC1. The exact sequence is proprietary.
Uniprot:: Q6ZN28
Synonyms:: 7A5;MACC1, MET transcriptional regulator;metastasis associated in colon cancer 1;metastasis-associated in colon cancer protein 1;putative binding protein 7a5;SH3 domain-containing protein 7a5;SH3BP4L
Extra Details:: MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM]