GTX130904
PTPRJ antibody
Cannot supply to this region.
- SKU:
- GTX130904
- Additional Names:
- protein tyrosine phosphatase receptor type J , CD148 , DEP1 , HPTPeta , R-PTP-ETA , SCC1
- Application:
- WB
- Concentration:
- 1.48 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the Extracellular domain of human PTPRJ. The exact sequence is proprietary.
- Uniprot:
- Q12913
- Synonyms:
- CD148;CD148 antigen;density-enhanced phosphatase 1;DEP-1;DEP1;HPTP eta;HPTPeta;human density enhanced phosphatase-1;protein tyrosine phosphatase, receptor type, J polypeptide;protein-tyrosine phosphatase eta;Protein-tyrosine phosphatase receptor type J;R-PTP-ETA;R-PTP-J;receptor-type tyrosine-protein phosphatase eta;SCC1;susceptibility to colon cancer 1, mouse, homolog of
- Extra Details:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice