GTX130679
LYRIC antibody
Cannot supply to this region.
- SKU:
- GTX130679
- Additional Names:
- metadherin , 3D3 , AEG-1 , AEG1 , LYRIC , LYRIC/3D3
- Application:
- WB, IHC-P, IF, ICC
- Concentration:
- 0.16 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Rat
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human LYRIC. The exact sequence is proprietary.
- Uniprot:
- Q86UE4
- Synonyms:
- 3D3;3D3/LYRIC;AEG-1;AEG1;astrocyte elevated gene 1;astrocyte elevated gene-1 protein;LYRIC;LYRIC/3D3;lysine-rich CEACAM1 co-isolated protein;Metadherin;metastasis adhesion protein;protein LYRIC
- Extra Details:
- Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.
- Shipping Conditions:
- Blue Ice