proBNP antibody [11D1]

Cannot supply to this region.

SKU:: GTX13059
Additional Names:: natriuretic peptide B , BNP
Application:: ELISA, WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 0.09% Sodium azide.
Immunogen:: Synthetic N-terminal pro brain natriuretic peptide (NT-proBNP), corresponding to amino acid residues a.a.r. 28-45. The peptides used for immunization were conjugated with carrier protein.
Clone:: 11D1
Uniprot:: P16860
Synonyms:: BNP;brain natriuretic factor prohormone;brain type natriuretic peptide;gamma-brain natriuretic peptide;Iso-ANP;natriuretic peptide precursor B;natriuretic peptides B;natriuretic protein;preproBNP;proBNP
Extra Details:: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]