GTX130499
ELAC2 antibody
Cannot supply to this region.
- SKU:
- GTX130499
- Additional Names:
- elaC ribonuclease Z 2 , COXPD17 , ELC2 , HPC2
- Application:
- WB, IHC-P, IP
- Concentration:
- 0.73 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human ELAC2. The exact sequence is proprietary.
- Uniprot:
- Q9BQ52
- Synonyms:
- COXPD17;elaC homolog 2;elaC homolog protein 2;elaC-like protein 2;ELC2;heredity prostate cancer protein 2;HPC2;putative prostate cancer susceptibility protein HPC2/ELAC2;ribonuclease Z 2;RNase Z 2;tRNA 3 endonuclease 2;tRNase Z (long form);tRNase Z 2;zinc phosphodiesterase ELAC protein 2
- Extra Details:
- The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice